Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.

Desmosomes are perturbed in a number of disease states - including genetic disorders, autoimmune and bacterial diseases. Here, we report unexpected changes in other cell-cell adhesion structures upon loss of desmosome function. We found that perturbation of desmosomes by either loss of the core desm...

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Bibliographic Details
Main Authors: Kaelyn Sumigray, Kang Zhou, Terry Lechler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090201?pdf=render