Functional and structural characterization of a eurytolerant calsequestrin from the intertidal teleost Fundulus heteroclitus.

Calsequestrins (CSQ) are high capacity, medium affinity, calcium-binding proteins present in the sarcoplasmic reticulum (SR) of cardiac and skeletal muscles. CSQ sequesters Ca²⁺ during muscle relaxation and increases the Ca²⁺-storage capacity of the SR. Mammalian CSQ has been well studied as a model...

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Bibliographic Details
Main Authors: A Carl Whittington, Tatyana E Nienow, Christi L Whittington, Timothy J Fort, Theresa J Grove
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511267?pdf=render