Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier

Abstract The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from entering the brain. An intact BBB is also critical for the maintenance of normal neuronal function. In cer...

Full description

Bibliographic Details
Main Authors: Jia Li, Meng Zheng, Olga Shimoni, William A. Banks, Ashley I. Bush, Jennifer R. Gamble, Bingyang Shi
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202101090