Signaling through polymerization and degradation: Analysis and simulations of T cell activation mediated by Bcl10.
The adaptive immune system serves as a potent and highly specific defense mechanism against pathogen infection. One component of this system, the effector T cell, facilitates pathogen clearance upon detection of specific antigens by the T cell receptor (TCR). A critical process in effector T cell ac...
Main Authors: | Leonard Campanello, Maria K Traver, Hari Shroff, Brian C Schaefer, Wolfgang Losert |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2021-05-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1007986 |
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