Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft

<p>Abstract</p> <p>Background</p> <p>Nucleic acids designed to modulate the expression of target proteins remain a promising therapeutic strategy in several diseases, including cancer. However, clinical success is limited by the lack of efficient intracellular delivery....

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Bibliographic Details
Main Authors: Baldi Alfonso, D'Angelo Carmen, Scarsella Marco, De Mori Roberta, Biroccio Annamaria, Spugnini Enrico P, Leonetti Carlo
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/125