Alcohol drinking alters stress response to predator odor via BNST kappa opioid receptor signaling in male mice

Alcohol drinking alters stress response to predator odor via BNST kappa opioid receptor signaling in male mice

Maladaptive responses to stress are a hallmark of alcohol use disorder, but the mechanisms that underlie this are not well characterized. Here, we show that kappa opioid receptor signaling in the bed nucleus of the stria terminalis (BNST) is a critical molecular substrate underlying abnormal stress...

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Bibliographic Details
Main Authors: Lara S Hwa, Sofia Neira, Meghan E Flanigan, Christina M Stanhope, Melanie M Pina, Dipanwita Pati, Olivia J Hon, Waylin Yu, Emily Kokush, Rachel Calloway, Kristen Boyt, Thomas L Kash
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
alcohol
stress
predator odor
dynorphin
kappa opioid receptor
norBNI
Online Access:https://elifesciences.org/articles/59709

Internet

https://elifesciences.org/articles/59709

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