Modeling a new water channel that allows SET9 to dimethylate p53.

Modeling a new water channel that allows SET9 to dimethylate p53.

SET9, a protein lysine methyltransferase, has been thought to be capable of transferring only one methyl group to target lysine residues. However, some reports have pointed out that SET9 can dimethylate Lys372 of p53 (p53-K372) and Lys4 of histone H3 (H3-K4). In order to understand how p53 can be di...

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Bibliographic Details
Main Authors: Qifeng Bai, Yulin Shen, Xiaojun Yao, Fang Wang, Yuping Du, Qin Wang, Nengzhi Jin, Jun Hai, Tiejun Hu, Jinbo Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625555/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625555/pdf/?tool=EBI

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