Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats

Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats

We investigated whether short term high fructose intake may induce early hepatic dysfunction in rats and to test whether allopurinol treatment may have beneficial effects. Twenty male Sprague-Dawley rats received 20% fructose in drinking water (10 treated with allopurinol and 10 received vehicle) an...

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Bibliographic Details
Main Authors: Fernando E. García-Arroyo, Fabiola Monroy-Sánchez, Itzel Muñoz-Jiménez, Guillermo Gonzaga, Ana Andrés-Hernando, Cecilia Zazueta, J. Gabriel Juárez-Rojas, Miguel A. Lanaspa, Richard J. Johnson, L. Gabriela Sánchez-Lozada
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biomolecules
Subjects:
hepatic steatosis
mitochondria
mitochondrial complex 1
Online Access:https://www.mdpi.com/2218-273X/9/10/601

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https://www.mdpi.com/2218-273X/9/10/601

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