Atypical scrapie isolates involve a uniform prion species with a complex molecular signature.

The pathobiology of atypical scrapie, a prion disease affecting sheep and goats, is still poorly understood. In a previous study, we demonstrated that atypical scrapie affecting small ruminants in Switzerland differs in the neuroanatomical distribution of the pathological prion protein (PrP(d)). To...

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Bibliographic Details
Main Authors: Dorothea R Götte, Sylvie L Benestad, Hubert Laude, Andreas Zurbriggen, Anna Oevermann, Torsten Seuberlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3214077?pdf=render