Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS‐275

Targeting foam cell formation in inflammatory brain diseases by the histone modifier MS‐275

Abstract Objective To assess class I‐histone deacetylase (HDAC) inhibition on formation of lipid‐accumulating, disease‐promoting phagocytes upon myelin load in vitro, relevant for neuroinflammatory disorders like multiple sclerosis (MS) and cerebral X‐linked adrenoleukodystrophy (X‐ALD). Methods Imm...

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Bibliographic Details
Main Authors: Bettina Zierfuss, Isabelle Weinhofer, Agnieszka Buda, Niko Popitsch, Lena Hess, Verena Moos, Simon Hametner, Stephan Kemp, Wolfgang Köhler, Sonja Forss‐Petter, Christian Seiser, Johannes Berger
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51200

Internet

https://doi.org/10.1002/acn3.51200

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