Conserved Endonuclease Function of Hantavirus L Polymerase

Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic “capping activity”. Hantaviruses therefore employ a “cap snatching”...

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Bibliographic Details
Main Authors: Sylvia Rothenberger, Giulia Torriani, Maria U. Johansson, Stefan Kunz, Olivier Engler
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/5/108