Mesenchymal Transformation: The Rosetta Stone of Glioblastoma Pathogenesis and Therapy Resistance

Mesenchymal Transformation: The Rosetta Stone of Glioblastoma Pathogenesis and Therapy Resistance

Abstract Despite decades of research, glioblastoma (GBM) remains invariably fatal among all forms of cancers. The high level of inter‐ and intratumoral heterogeneity along with its biological location, the brain, are major barriers against effective treatment. Molecular and single cell analysis iden...

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Bibliographic Details
Main Authors: Zulfikar Azam, Shing‐Shun Tony TO, Bakhos A. Tannous
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Advanced Science
Subjects:
clinical outcome
glioblastoma (GBM)
mesenchymal transition
molecular subtypes
therapy responses
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202002015

Internet

https://doi.org/10.1002/advs.202002015

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