Norfloxacin mixed solvency based solid dispersions: An in-vitro and in-vivo investigation

Norfloxacin (NF) is a synthetic fluoro-quinolone molecule that is used for the treatment of urinary tract infections. However, due to its poor aqueous solubility, it has low oral bioavailability. The aim of the present study was to improve the aqueous solubility and dissolution profile of NF by form...

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Bibliographic Details
Main Authors: Ravindra Kamble, Sumeet Sharma, Piyush Mehta
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Journal of Taibah University for Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1658365517300122