SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces.

SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces.

Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such "intrinsic plasticity" in behavioral learning in a mouse model that allows us to detect specific consequences of...

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Bibliographic Details
Main Authors: Giorgio Grasselli, Henk-Jan Boele, Heather K Titley, Nora Bradford, Lisa van Beers, Lindsey Jay, Gerco C Beekhof, Silas E Busch, Chris I De Zeeuw, Martijn Schonewille, Christian Hansel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000596

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https://doi.org/10.1371/journal.pbio.3000596

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