Long non-coding RNA HOTAIR promotes UVB-induced apoptosis and inflammatory injury by up-regulation of PKR in keratinocytes

Excessive exposure to ultraviolet (UV) rays can cause damage of the skin and may induce cancer, immunosuppression, photoaging, and inflammation. The long non-coding RNA (lncRNA) HOX antisense intergenic RNA (HOTAIR) is involved in multiple human biological processes. However, its role in UVB-induced...

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Bibliographic Details
Main Authors: Guo Liu, Wenhao Zhang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-06-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
PKR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000800607&lng=en&tlng=en