Pathophysiological relationship between hypoxia associated oxidative stress, Epithelial-mesenchymal transition, stemness acquisition and alteration of Shh/ Gli-1 axis during oral sub-mucous fibrosis and oral squamous cell carcinoma

Pathophysiological relationship between hypoxia associated oxidative stress, Epithelial-mesenchymal transition, stemness acquisition and alteration of Shh/ Gli-1 axis during oral sub-mucous fibrosis and oral squamous cell carcinoma

Oral sub-mucous fibrosis (OSF) is a pathophysiological state of oral cavity or oropharynx having a high chance of conversion to oral squamous cell carcinoma (OSCC). It involves fibrotic transformation of sub-epithelial matrix along with epithelial abnormalities. The present work aims to unveil the m...

Full description

Bibliographic Details
Main Authors: Ritam Chatterjee, Biswajoy Ghosh, Mousumi Mandal, Debaleena Nawn, Satarupa Banerjee, Mousumi Pal, Ranjan Rashmi Paul, Swarnabindu Banerjee, Jyotirmoy Chatterjee
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:European Journal of Cell Biology
Subjects:
Oral sub-mucous fibrosis
Oral squamous cell carcinoma
Oxidative stress
Epithelial-mesenchymal transition
Stemness
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933520300856

Internet

http://www.sciencedirect.com/science/article/pii/S0171933520300856

Similar Items