Imbalanced amplification: A mechanism of amplification and suppression from local imbalance of excitation and inhibition in cortical circuits.

Understanding the relationship between external stimuli and the spiking activity of cortical populations is a central problem in neuroscience. Dense recurrent connectivity in local cortical circuits can lead to counterintuitive response properties, raising the question of whether there are simple ar...

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Bibliographic Details
Main Authors: Christopher Ebsch, Robert Rosenbaum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006048