miRNAs 144-3p, 34a-5p, and 206 are a useful signature for distinguishing uterine leiomyosarcoma from other smooth muscle tumors

Abstract Background Leiomyosarcoma (LMS) is a rare uterine neoplasm that has a high mortality rate and no specific treatment. The origin of LMS remains unknown; although, it is hypothesized that LMS arises from the malignant transformation of a degenerated uterine leiomyoma (LM). LMs are the most co...

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Main Authors: Beatriz Nunes Schiavon, Katia Candido Carvalho, Cláudia Malheiros Coutinho-Camillo, Glauco Baiocchi, Renan Valieris, Rodrigo Drummond, Israel Tojal da Silva, Louise De Brot, Fernando Augusto Soares, Isabela Werneck da Cunha
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Surgical and Experimental Pathology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42047-019-0032-0