miR-26 Induces Apoptosis and Inhibits Autophagy in Non-small Cell Lung Cancer Cells by Suppressing TGF-β1-JNK Signaling Pathway

miR-26 Induces Apoptosis and Inhibits Autophagy in Non-small Cell Lung Cancer Cells by Suppressing TGF-β1-JNK Signaling Pathway

Non-small cell lung cancer (NSCLC) is one of the causes of cancer mortality worldwide. The role of miR-26 in the development and progression of NSCLC remains largely unknown. In this study we found an abnormal expression of miR-26 in human NSCLC tissues. It was found that miR-26 mimics induced cell...

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Bibliographic Details
Main Authors: Yi He, Hao Liu, Lianyong Jiang, Bi Rui, Ju Mei, Haibo Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
NSCLC
miR-26
TGF-β
JNK
apoptosis
autophagy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01509/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01509/full

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