Preparation and characterization of a novel aspirin derivative with anti-thrombotic and gastric mucosal protection properties.

The use of acetylsalicylic acid (ASP) is limited by its adverse effects, especially the effect on the gastric mucosa. To address this problem, we synthesized a derivative form of ASP, prepared by modification of ASP with nano-hydroxyapatite (a kind of inorganic particle containing Ca(2+)). The deriv...

Full description

Bibliographic Details
Main Authors: Xi-E Zhen, Ming Zong, Sai-Nan Gao, Yong-Gang Cao, Lei Jiang, Shu-Xin Chen, Kuan Wang, Shi-Qin Sun, Hai-Sheng Peng, Yu-Hua Bai, Sen Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4043976?pdf=render