Combined renin-angiotensin system blockade and dietary sodium restriction impairs cardiomyocyte contractility

Introduction Blockade of the renin-angiotensin system (RAS) by combined angiotensin-converting enzyme inhibitor and angiotensin type 1 receptor (AT 1 ) antagonist treatment with reduced dietary sodium intake produces suppression of cardiac growth and regression of cardiac hypertrophy. The purpose of...

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Bibliographic Details
Main Authors: Petcharat Trongtorsak, Trefor O Morgan, Lea MD Delbridge
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2003-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2003.035