Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway

Antioxidant Ascorbic Acid Modulates NLRP3 Inflammasome in LPS-G Treated Oral Stem Cells through NFκB/Caspase-1/IL-1β Pathway

Human gingival mesenchymal stem cells (hGMSCs) and endothelial committed hGMSCs (e-hGMSCs) have considerable potential to serve as an in vitro model to replicate the inflammation sustained by <i>Porphyromonas gingivalis</i> in periodontal and cardiovascular diseases. The present study ai...

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Bibliographic Details
Main Authors: Jacopo Pizzicannella, Luigia Fonticoli, Simone Guarnieri, Guya D. Marconi, Thangavelu Soundara Rajan, Oriana Trubiani, Francesca Diomede
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
periodontal disease
NLRP3 inflammasome
ascorbic acid
gingival mesenchymal stem cells
<i>Porphyromonas gingivalis</i>
Online Access:https://www.mdpi.com/2076-3921/10/5/797

Internet

https://www.mdpi.com/2076-3921/10/5/797

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