Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma

Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma

Abstract Primary hepatocellular carcinoma (HCC) mainly develops in subjects chronically infected with hepatitis B (HBV) and C (HCV) viruses through a multistep process characterized by the accumulation of genetic alterations in the human genome. Nucleotide changes in coding regions (i.e. TP53, CTNNB...

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Bibliographic Details
Main Authors: Francesca Pezzuto, Luigi Buonaguro, Franco M. Buonaguro, Maria Lina Tornesello
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Infectious Agents and Cancer
Subjects:
Telomerase
TERT promoter mutations
Hepatocellular carcinoma
Hepatitis B virus
Hepatitis C virus
Online Access:http://link.springer.com/article/10.1186/s13027-017-0138-5

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http://link.springer.com/article/10.1186/s13027-017-0138-5

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