Enzymatic assays for the diagnosis of bradykinin-dependent angioedema.

<h4>Background</h4>The kinins (primarily bradykinin, BK) represent the mediators responsible for local increase of vascular permeability in hereditary angioedema (HAE), HAE I-II associated with alterations of the SERPING1 gene and HAE with normal C1-Inhibitor function (HAE-nC1INH). Besid...

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Main Authors: Federica Defendi, Delphine Charignon, Arije Ghannam, Remi Baroso, Françoise Csopaki, Marion Allegret-Cadet, Denise Ponard, Bertrand Favier, Sven Cichon, Brigitte Nicolie, Olivier Fain, Ludovic Martin, Christian Drouet, National Reference Centre for Angioedema CREAK
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23940538/?tool=EBI