Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.

BACKGROUND:Breast cancer cell lines have been used widely to investigate breast cancer pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease, and it is important to understand how well and which cell lines best model that diversity. In particular, microarray studies ha...

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Bibliographic Details
Main Authors: Jessica Kao, Keyan Salari, Melanie Bocanegra, Yoon-La Choi, Luc Girard, Jeet Gandhi, Kevin A Kwei, Tina Hernandez-Boussard, Pei Wang, Adi F Gazdar, John D Minna, Jonathan R Pollack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2702084?pdf=render