Ex Vivo Expansion of Functional Human UCB-HSCs/HPCs by Coculture with AFT024-hkirre Cells

Kiaa1867 (human Kirre, hKirre) has a critical role in brain development and/or maintenance of the glomerular slit diaphragm in kidneys. Murine homolog of this gene, mKirre expressed in OP9 and AFT024 cells could support hematopoietic stem cells/hematopoietic progenitor cells (HSC/HPC) expansion in v...

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Bibliographic Details
Main Authors: Muti ur Rehman Khan, Ijaz Ali, Wei Jiao, Yun Wang, Saima Masood, Muhammad Zubair Yousaf, Aqeel Javaid, Shafique Ahmad, Meifu Feng
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/412075