Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.

Oxidative stress is thought to compromise muscle contractility. However, administration of generic antioxidants has failed to convincingly improve performance during exhaustive exercise. One possible explanation may relate to the inability of the supplemented antioxidants to effectively eliminate ex...

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Bibliographic Details
Main Authors: Dejia Li, Yi Lai, Yongping Yue, Peter S Rabinovitch, Chady Hakim, Dongsheng Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2723912?pdf=render