Platycodon grandiflorus enhances the effect of DDP against lung cancer by down regulating PI3K/Akt signaling pathway

Cisplatin (DDP) is a first-line drug for non-small cell lung cancer (NSCLC), but its efficacy and applications are constrained by intolerance and serious side effects. Platycodon grandiflorus (PG) is usually used as lung medicinal drug to enhance other drug’s effect on lung diseases. Therefore, pres...

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Bibliographic Details
Main Authors: Yang Li, Yayun Wu, Qi Xia, Ya Zhao, Ruizhi Zhao, Shigui Deng
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
DDP
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219332081