Bacterial ligands generated in a phagosome are targets of the cytosolic innate immune system.
Macrophages are permissive hosts to intracellular pathogens, but upon activation become microbiocidal effectors of innate and cell-mediated immunity. How the fate of internalized microorganisms is monitored by macrophages, and how that information is integrated to stimulate specific immune responses...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-03-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1839167?pdf=render |