Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation

Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation

Excessive proliferation and inflammation of synovial fibroblasts accelerate and decorate the pathological process of rheumatoid arthritis (RA). Sigesbeckia orientalis L. (SO) is one of the main plant sources for Sigesbeckiae Herba (SH) which has been used traditionally in treating various forms of a...

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Bibliographic Details
Main Authors: Ke-Gang Linghu, Shi Hang Xiong, Guan Ding Zhao, Tian Zhang, Wei Xiong, Mingming Zhao, Xiang-Chun Shen, Wei Xu, Zhaoxiang Bian, Yitao Wang, Hua Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
synovial hyperplasia
inflammation
Sigesbeckia orientalis L.
SW982
MH7A
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.547913/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.547913/full

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