B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy.

B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy.

B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn's disease.To elucidate the involvement of B cells in Crohn's disease, we here performed an 'in depth' analysis of intestinal and blood B-cells in this c...

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Bibliographic Details
Main Authors: Wilhelmina M C Timmermans, Jan A M van Laar, Tim B van der Houwen, Lieke S J Kamphuis, Sophinus J W Bartol, King H Lam, Rob J Ouwendijk, Miles P Sparrow, Peter R Gibson, P Martin van Hagen, Menno C van Zelm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4965034?pdf=render

Internet

http://europepmc.org/articles/PMC4965034?pdf=render

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