Changes of PLCγ1/IP3R/CaMKⅡ protein expression and dendritic spine density in hippocampus of VPA-induced autistic young mice

Changes of PLCγ1/IP3R/CaMKⅡ protein expression and dendritic spine density in hippocampus of VPA-induced autistic young mice

Objective To investigate expression changes of phospholipase C-γ1 (PLCγ1)/inositol triphosphate receptor (IP3R)/calmodulin-dependent kinase Ⅱ (CaMKⅡ) and density of dendritic spine in the hippocampus of autism model mice induced by sodium valproate (VPA). Methods Pregnant C57 mouse was given intrape...

Full description

Bibliographic Details
Main Authors: ZHAO Yu, WANG Yan, ZHENG Wenxia, HU Yuling, ANG Xiaoqing, CHEN Di, LI Yingbo, YANG Rong, WANG Shali
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-07-01
Series:Di-san junyi daxue xuebao
Subjects:
autism spectrum disorder
sodium valproate
hippocampus
phospholipase c-gamma1
1
4
5-trisphosphate receptor
calmodulin-dependent protein kinase ⅱ
dendritic spines
postsynaptic density-95
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202002189.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202002189.htm

Similar Items