Safety of Herbal Medicinal Products: Echinacea and Selected Alkylamides Do Not Induce CYP3A4 mRNA Expression

A major safety concern with the use of herbal medicinal products (HMP) is their interactions with conventional medicines, which are often mediated via the cytochrome P450 (CYP) system. Echinacea is a widely used over-the-counter HMP, with proven immunomodulatory properties. Its increasing use makes...

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Bibliographic Details
Main Authors: Maryam Modarai, Elisabete Silva, Andy Suter, Michael Heinrich, Andreas Kortenkamp
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1093/ecam/nep174