Blood–brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

Blood–brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis

Postmortem MRI-guided tissue sampling significantly enhances the yield of MS lesions in autopsy material, but so far it is unknown whether abnormalities concur with blood–brain barrier alterations. Here we sampled MS lesions with focal and diffuse abnormalities (diffusely abnormal white matter; DAWM...

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Bibliographic Details
Main Authors: Catharina M.P. Vos, Jeroen J.G. Geurts, Lisette Montagne, Elise S. van Haastert, Lars Bö, Paul van der Valk, Frederik Barkhof, Helga E. de Vries
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Neurobiology of Disease
Subjects:
Multiple sclerosis
Blood–brain barrier
Basement membrane
Postmortem MRI
Leukocyte infiltration
Virchow–Robin space
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001658

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http://www.sciencedirect.com/science/article/pii/S0969996105001658

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