Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trial.

Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trial.

<h4>Background</h4>Human noroviruses (NoVs) are the primary cause of acute gastroenteritis and are characterized by antigenic variation between genogroups and genotypes and antigenic drift of strains within the predominant GII.4 genotype. In the context of this diversity, an effective No...

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Bibliographic Details
Main Authors: Lisa C Lindesmith, Martin T Ferris, Clancy W Mullan, Jennifer Ferreira, Kari Debbink, Jesica Swanstrom, Charles Richardson, Robert R Goodwin, Frank Baehner, Paul M Mendelman, Robert F Bargatze, Ralph S Baric
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001807

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https://doi.org/10.1371/journal.pmed.1001807

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