Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth
Changes in glucose metabolism can lead to tumor development, but the involvement of splicing factors is unclear. Here, the authors screened for SR proteins and identified SRSF5 stability is enhanced in response to glucose elevation to promote alternative splicing of CCAR1 which facilitates tumor gro...
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Bibliographic Details
| Main Authors: |
Yuhan Chen,
Qingyang Huang,
Wen Liu,
Qiong Zhu,
Chun-Ping Cui,
Liang Xu,
Xing Guo,
Ping Wang,
Jingwen Liu,
Guanglong Dong,
Wenyi Wei,
Cui Hua Liu,
Zhichun Feng,
Fuchu He,
Lingqiang Zhang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-04815-3
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