Application of CRISPR/Cas9-Based Reverse Genetics in <i>Leishmania braziliensis</i>: Conserved Roles for HSP100 and HSP23

Application of CRISPR/Cas9-Based Reverse Genetics in <i>Leishmania braziliensis</i>: Conserved Roles for HSP100 and HSP23

The protozoan parasite <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis (L. braziliensis</i>) is the main cause of human tegumentary leishmaniasis in the New World, a disease affecting the skin and/or mucosal tissues. Despite its importance, the study of the uni...

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Bibliographic Details
Main Authors: Vanessa Adaui, Constanze Kröber-Boncardo, Christine Brinker, Henner Zirpel, Julie Sellau, Jorge Arévalo, Jean-Claude Dujardin, Joachim Clos
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
<i>Leishmania braziliensis</i>
reverse genetics
CRISPR–Cas9
gene targeting
phenotyping
heat shock proteins
Online Access:https://www.mdpi.com/2073-4425/11/10/1159

Internet

https://www.mdpi.com/2073-4425/11/10/1159

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