Immunomodulatory Effect of MSC on B Cells Is Independent of Secreted Extracellular Vesicles

Mesenchymal stem or stromal cells (MSC) have proven immunomodulatory properties toward B cell activation and induce regulatory B cells (Breg), through a dual mechanism of action that relies both on cell contact and secreted factors. One of them are MSC-derived extracellular vesicles (EVs), membrane...

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Bibliographic Details
Main Authors: Laura Carreras-Planella, Marta Monguió-Tortajada, Francesc Enric Borràs, Marcella Franquesa
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01288/full