Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.

Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.

The mechanism that specifies olfactory sensory neurons to express only one odorant receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood. Here, we describe the first comprehensive analysis of OR expression regulation in Drosophila. A systematic, RNAi-mediate...

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Bibliographic Details
Main Authors: Shadi Jafari, Liza Alkhori, Alexander Schleiffer, Anna Brochtrup, Thomas Hummel, Mattias Alenius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3302810?pdf=render

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