Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.

The mechanism that specifies olfactory sensory neurons to express only one odorant receptor (OR) from a large repertoire is critical for odor discrimination but poorly understood. Here, we describe the first comprehensive analysis of OR expression regulation in Drosophila. A systematic, RNAi-mediate...

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Bibliographic Details
Main Authors: Shadi Jafari, Liza Alkhori, Alexander Schleiffer, Anna Brochtrup, Thomas Hummel, Mattias Alenius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3302810?pdf=render