Importance of <it>TP53 codon 72 and intron 3 duplication 16bp </it>polymorphisms in prediction of susceptibility on breast cancer

<p>Abstract</p> <p>Background</p> <p><it>TP53 </it>is one of major tumour suppressor genes being essential in preservation of genome integrity. Two very common polymorphisms have been demonstrated to contribute to cancer susceptibility and tumour behaviour....

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Bibliographic Details
Main Authors: Medeiros Rui, Cameselle-Teijeiro Jorge, Rodrigues Helena, Pereira Deolinda, Pinto Daniela, Costa Sandra, Schmitt Fernando
Format: Article
Language:English
Published: BMC 2008-01-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/32