The potential role of RNA N6-methyladenosine in Cancer progression

Abstract N6-methyladenosine (m6A) is considered the most common, abundant, and conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA). m6A is installed by m6A methyltransferases (METTL3/14, WTAP, RBM15/15B, VIRMA and ZC3H13, termed “writers”), removed by demethylas...

Full description

Bibliographic Details
Main Authors: Tianyi Wang, Shan Kong, Mei Tao, Shaoqing Ju
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-020-01204-7