Prediction and interpretation of miRNA-disease associations based on miRNA target genes using canonical correlation analysis

Abstract Background It has been shown that the deregulation of miRNAs is associated with the development and progression of many human diseases. To reduce time and cost of biological experiments, a number of algorithms have been proposed for predicting miRNA-disease associations. However, the existi...

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Bibliographic Details
Main Authors: Hailin Chen, Zuping Zhang, Dayi Feng
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2998-8