Identification of novel high-frequency DNA methylation changes in breast cancer.

Identification of novel high-frequency DNA methylation changes in breast cancer.

Recent data have revealed that epigenetic alterations, including DNA methylation and chromatin structure changes, are among the earliest molecular abnormalities to occur during tumorigenesis. The inherent thermodynamic stability of cytosine methylation and the apparent high specificity of the altera...

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Bibliographic Details
Main Authors: Jared M Ordway, Muhammad A Budiman, Yulia Korshunova, Rebecca K Maloney, Joseph A Bedell, Robert W Citek, Blaire Bacher, Seth Peterson, Tracy Rohlfing, Jacqueline Hall, Robert Brown, Nathan Lakey, Rebecca W Doerge, Robert A Martienssen, Jorge Leon, John D McPherson, Jeffrey A Jeddeloh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2117343?pdf=render

Internet

http://europepmc.org/articles/PMC2117343?pdf=render

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