Identification of Conserved ABC Importers Necessary for Intracellular Survival of Legionella pneumophila in Multiple Hosts

Identification of Conserved ABC Importers Necessary for Intracellular Survival of Legionella pneumophila in Multiple Hosts

It is established that the human pathogen Legionella pneumophila becomes significantly augmented for infection of macrophages after intracellular growth in amoebae when compared to like-strains cultivated in laboratory media. Based on this observation, we reasoned that the most critical virulence de...

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Bibliographic Details
Main Authors: Amrita Lama, Samuel L. Drennan, Rudd C. Johnson, Grace L. Rubenstein, Eric D. Cambronne
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Legionella
pathogenesis
transposon mutagenesis
Acanthamoeba castellanii
macrophage
Dot/Icm T4b secretion system
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00485/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00485/full

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