Integrative clustering of multi-level 'omic data based on non-negative matrix factorization algorithm.

Integrative analyses of high-throughput 'omic data, such as DNA methylation, DNA copy number alteration, mRNA and protein expression levels, have created unprecedented opportunities to understand the molecular basis of human disease. In particular, integrative analyses have been the cornerstone...

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Bibliographic Details
Main Authors: Prabhakar Chalise, Brooke L Fridley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5411077?pdf=render