Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection.

Protection at the peak of Plasmodium chabaudi blood-stage malaria infection is provided by CD4 T cells. We have shown that an increase in Th1 cells also correlates with protection during the persistent phase of malaria; however, it is unclear how these T cells are maintained. Persistent malaria infe...

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Bibliographic Details
Main Authors: Michael M Opata, Samad A Ibitokou, Victor H Carpio, Karis M Marshall, Brian E Dillon, Jordan C Carl, Kyle D Wilson, Christine M Arcari, Robin Stephens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5908200?pdf=render