Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma

Allergic asthma is a chronic, complex inflammatory disease of the airway. Despite extensive studies on the immunomodulation of T helper (Th) cell pathways (i.e., Th1 and Th2) in asthma, little is known about the effects of Th17 pathway modulation, particularly that involving peroxisome proliferator-...

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Main Authors: Moacyr Jesus Barreto de Melo Rêgo, Adriana Azoubel-Antunes, Mariana Brayner-Cavalcanti Freire Bezerra, Michelly Cristiny Pereira, Juliana Cruz da Silva, Thiago Ubiratan Lins e Lins, Emanuel Sávio Cavalcanti Sarinho, Cézar Augusto da Cruz Amorim, Maria do Carmo Alves de Lima, Marina Rocha Galdino-Pitta, Ivan da Rocha Pitta, Maira Galdino da Rocha Pitta
Format: Article
Language:English
Published: Universidade de São Paulo 2018-11-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300602&lng=en&tlng=en