Expression profile of the matricellular protein periostin in paediatric inflammatory bowel disease

Abstract The precise role of periostin, an extra-cellular matrix protein, in inflammatory bowel disease (IBD) is unclear. Here, we investigated periostin in paediatric IBD including its relationship with disease activity, clinical outcomes, genomic variation and expression in the colonic tissue. Pla...

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Bibliographic Details
Main Authors: Tracy Coelho, Eva Sonnenberg-Riethmacher, Yifang Gao, Enrico Mossotto, Alisher Khojanazarov, Annie Griffin, Saida Mukanova, Aiymkul Ashimkhanova, Rachel Haggarty, Anton Borissenko, James J. Ashton, Imogen S. Stafford, Akshay Batra, Nadeem A. Afzal, Michael P. Stanton, Bhumita Vadgama, Kapura Adrisova, Robert M. Beattie, Anthony P. Williams, Sarah Ennis, Dieter Riethmacher
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85096-7