Impact of renal function-based anti-tuberculosis drug dosage adjustment on efficacy and safety outcomes in pulmonary tuberculosis complicated with chronic kidney disease

Impact of renal function-based anti-tuberculosis drug dosage adjustment on efficacy and safety outcomes in pulmonary tuberculosis complicated with chronic kidney disease

Abstract Background Dosages of anti-tuberculosis (TB) drugs are recommended to be adjusted according to renal function for patients complicated with chronic kidney disease (CKD). However, the efficacy and safety outcomes of such renal function-based dosage adjustments are not fully elucidated. Metho...

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Bibliographic Details
Main Authors: Nayuta Saito, Yutaka Yoshii, Yugo Kaneko, Akio Nakashima, Tsugumi Horikiri, Zenya Saito, Sho Watanabe, Akira Kinoshita, Keisuke Saito, Kazuyoshi Kuwano
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Infectious Diseases
Subjects:
Chronic renal insufficiency
Drug-related side effects
Glomerular filtration rate
Hospital mortality
Pulmonary tuberculosis
Online Access:http://link.springer.com/article/10.1186/s12879-019-4010-7

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http://link.springer.com/article/10.1186/s12879-019-4010-7

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